Two sample MR report
NQO2_Alveolar Macrophages against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.0345507 | 1.2975381 | 0.9830521 |
| Weighted median | 3 | 0.0387800 | 0.0141531 | 0.0061433 |
| Inverse variance weighted | 3 | 0.0388205 | 0.0110683 | 0.0004526 |
| Simple mode | 3 | 0.0386896 | 0.0156083 | 0.1314202 |
| Weighted mode | 3 | 0.0386608 | 0.0158988 | 0.1355614 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0000866 | 1 | 0.9925737 |
| Inverse variance weighted | 0.0032844 | 2 | 0.9983592 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0519412 | 0.9185233 | 0.9640384 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 3.02e-05 | 0 | TRUE | 0.60567 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
